p(INTERPRO:"Kinesin motor domain") association p(RGD:Snca)

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PubMed:16176937

By immunoprecipitation, we also found that tau and alpha-synuclein are each associated, either directly or indirectly with complexes containing the fast anterograde motor kinesin-1, and alpha-synuclein is also present in a complex with the fast retrograde motor dynein.In this study, we observed marked differences in the relative associations of tau and alpha-synuclein directly with molecular motors because tau interacts with a kinesin-1 complex binding to KLC1 and KLC2, whereas alpha-synuclein did not bind to either KLC1 or KLC2 under our experimental conditions.

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• p(RGD:Snca) association p(INTERPRO:"Kinesin motor domain")

Uberon

brain

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