p(HGNC:CHRNA3, var("?")) positiveCorrelation path(MESH:"Opioid-Related Disorders")

View Subject View Object

PubMed:21482353

Single-nucleotide polymorphisms found in the human alpha5, alpha3, beta4 gene cluster are associated with nicotine dependence and its age-dependent onset; number of cigarettes smoked per day and ‘‘pleasurable buzz’’ elicited by smoking; alcoholism, sensitivity to the depressant effects of alcohol, and age of alcohol initiation; cocaine dependence; opioid dependence; lung cancer; and cognitive flexibility (Erlich et al., 2010; Hansen et al., 2010; Improgo et al., 2010; Saccone et al., 2010; Zhang et al., 2010)

Related Edges 35

• bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA5, var("?"))
• bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA3, var("?"))
• bp(GO:cognition) positiveCorrelation p(HGNC:CHRNB4, var("?"))
• p(HGNC:CHRNA3, var("?")) positiveCorrelation path(MESH:"Tobacco Use Disorder")
• p(HGNC:CHRNA3, var("?")) positiveCorrelation path(MESH:Alcoholism)
• p(HGNC:CHRNA3, var("?")) positiveCorrelation path(MESH:"Cocaine-Related Disorders")
• p(HGNC:CHRNA3, var("?")) positiveCorrelation path(MESH:"Lung Neoplasms")
• p(HGNC:CHRNA3, var("?")) positiveCorrelation bp(GO:cognition)
• p(HGNC:CHRNA5, var("?")) positiveCorrelation path(MESH:"Tobacco Use Disorder")
• p(HGNC:CHRNA5, var("?")) positiveCorrelation path(MESH:Alcoholism)
• p(HGNC:CHRNA5, var("?")) positiveCorrelation path(MESH:"Cocaine-Related Disorders")
• p(HGNC:CHRNA5, var("?")) positiveCorrelation path(MESH:"Opioid-Related Disorders")
• p(HGNC:CHRNA5, var("?")) positiveCorrelation path(MESH:"Lung Neoplasms")
• p(HGNC:CHRNA5, var("?")) positiveCorrelation bp(GO:cognition)
• p(HGNC:CHRNB4, var("?")) positiveCorrelation path(MESH:"Tobacco Use Disorder")
• p(HGNC:CHRNB4, var("?")) positiveCorrelation path(MESH:Alcoholism)
• p(HGNC:CHRNB4, var("?")) positiveCorrelation path(MESH:"Cocaine-Related Disorders")
• p(HGNC:CHRNB4, var("?")) positiveCorrelation path(MESH:"Opioid-Related Disorders")
• p(HGNC:CHRNB4, var("?")) positiveCorrelation path(MESH:"Lung Neoplasms")
• p(HGNC:CHRNB4, var("?")) positiveCorrelation bp(GO:cognition)
• path(MESH:"Cocaine-Related Disorders") positiveCorrelation p(HGNC:CHRNA5, var("?"))
• path(MESH:"Cocaine-Related Disorders") positiveCorrelation p(HGNC:CHRNA3, var("?"))
• path(MESH:"Cocaine-Related Disorders") positiveCorrelation p(HGNC:CHRNB4, var("?"))
• path(MESH:"Lung Neoplasms") positiveCorrelation p(HGNC:CHRNA5, var("?"))
• path(MESH:"Lung Neoplasms") positiveCorrelation p(HGNC:CHRNA3, var("?"))
• path(MESH:"Lung Neoplasms") positiveCorrelation p(HGNC:CHRNB4, var("?"))
• path(MESH:"Opioid-Related Disorders") positiveCorrelation p(HGNC:CHRNA5, var("?"))
• path(MESH:"Opioid-Related Disorders") positiveCorrelation p(HGNC:CHRNA3, var("?"))
• path(MESH:"Opioid-Related Disorders") positiveCorrelation p(HGNC:CHRNB4, var("?"))
• path(MESH:"Tobacco Use Disorder") positiveCorrelation p(HGNC:CHRNA5, var("?"))
• path(MESH:"Tobacco Use Disorder") positiveCorrelation p(HGNC:CHRNA3, var("?"))
• path(MESH:"Tobacco Use Disorder") positiveCorrelation p(HGNC:CHRNB4, var("?"))
• path(MESH:Alcoholism) positiveCorrelation p(HGNC:CHRNA5, var("?"))
• path(MESH:Alcoholism) positiveCorrelation p(HGNC:CHRNA3, var("?"))
• path(MESH:Alcoholism) positiveCorrelation p(HGNC:CHRNB4, var("?"))

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---