1. Catalog
  2. Namespaces
  3. Experimental Factor Ontology (EFO)
  4. MEF cell line

MEF cell line

Name
MEF cell line
Namespace Keyword
CellLine
Namespace
Experimental Factor Ontology (EFO)
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell-line/cell-line-20170511.belanno

Sample Annotated Edges 5

p(HGNC:USP14) decreases act(p(FPLX:Proteasome)) View Subject | View Object

The DUB USP14 suppresses turnover of Tau and TDP-43 in mouse embryonic fibroblasts (MEFs) by impairing the protea-some; PubMed:25784053

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
MEF cell line
Cell Ontology (CL)
motor neuron

p(HGNC:USP14) decreases deg(p(HGNC:MAPT)) View Subject | View Object

The DUB USP14 suppresses turnover of Tau and TDP-43 in mouse embryonic fibroblasts (MEFs) by impairing the protea-some; PubMed:25784053

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
MEF cell line
Cell Ontology (CL)
motor neuron

a(PUBCHEM:675434) causesNoChange p(FPLX:Proteasome) View Subject | View Object

Treatment with IU1 reduced the levels of Tau, TDP-43, and ataxin-3 in MEFs in a USP14-dependent manner and independently of changes in proteasome levels or composition (147). PubMed:25784053

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
MEF cell line
Cell Ontology (CL)
motor neuron

a(PUBCHEM:675434) decreases p(HGNC:ATXN3) View Subject | View Object

Treatment with IU1 reduced the levels of Tau, TDP-43, and ataxin-3 in MEFs in a USP14-dependent manner and independently of changes in proteasome levels or composition (147). PubMed:25784053

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
MEF cell line
Cell Ontology (CL)
motor neuron

p(HGNC:USP14) decreases deg(p(HGNC:TARDBP)) View Subject | View Object

The DUB USP14 suppresses turnover of Tau and TDP-43 in mouse embryonic fibroblasts (MEFs) by impairing the protea-some; PubMed:25784053

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
MEF cell line
Cell Ontology (CL)
motor neuron

Showing 5 of 8 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.