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  4. Extracellular Space

Extracellular Space

Name
Extracellular Space
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00018) View Subject | View Object

Extracellular deposition of amyloid-β aggregates, the main constituent of senile plaques, is considered to be a pathological hallmark of Alzheimer’s disease that contributes to neuronal dysfunction and behavioural changes PubMed:30046111

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Extracellular Space

a(HBP:HBP00018) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

Extracellular deposition of amyloid-β aggregates, the main constituent of senile plaques, is considered to be a pathological hallmark of Alzheimer’s disease that contributes to neuronal dysfunction and behavioural changes PubMed:30046111

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Extracellular Space

a(HBP:HBP00018) decreases bp(GO:"neuron cellular homeostasis") View Subject | View Object

Extracellular deposition of amyloid-β aggregates, the main constituent of senile plaques, is considered to be a pathological hallmark of Alzheimer’s disease that contributes to neuronal dysfunction and behavioural changes PubMed:30046111

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Extracellular Space

a(HBP:HBP00018) increases path(MESH:"Problem Behavior") View Subject | View Object

Extracellular deposition of amyloid-β aggregates, the main constituent of senile plaques, is considered to be a pathological hallmark of Alzheimer’s disease that contributes to neuronal dysfunction and behavioural changes PubMed:30046111

Appears in Networks:
Annotations
Confidence
Medium
MeSH
Extracellular Space

a(CHEBI:"calcium(2+)") regulates act(p(FPLX:CHRN)) View Subject | View Object

Although calcium modulation can act intracellularly, nAChRs also are allosterically modulated by extracellular calcium, leading to dramatic changes in the channel opening probability (Amador & Dani, 1995; Mulle, Lena, & Changeux, 1992; Vernino et al., 1992). PubMed:26472524

Appears in Networks:
Annotations
MeSH
Extracellular Space

Showing 5 of 41 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.