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complex(a(MESH:Proteins), p(FPLX:HSP90))

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Components

Appears in Networks 1

Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies v1.0.0

In-Edges 1

a(CHEBI:"Hsp90 inhibitor") increases complex(a(MESH:Proteins), p(FPLX:HSP90)) View Subject | View Object

Moreover, these compounds were found to prolong binding of Hsp90 to a model substrate, which was sufficient to promote its degradation [142] PubMed:21882945

Appears in Networks:

Out-Edges 3

complex(a(MESH:Proteins), p(FPLX:HSP90)) hasComponent a(MESH:Proteins) View Subject | View Object

Appears in Networks:

complex(a(MESH:Proteins), p(FPLX:HSP90)) increases deg(a(MESH:Proteins)) View Subject | View Object

Moreover, these compounds were found to prolong binding of Hsp90 to a model substrate, which was sufficient to promote its degradation [142] PubMed:21882945

Appears in Networks:

complex(a(MESH:Proteins), p(FPLX:HSP90)) hasComponent p(FPLX:HSP90) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.