Evidences a(MESH:Neurons) to p(HGNC:MAPT)

In addition, stimulating neuronal activity in either cultured neurons or in vivo also enhances tau release

this observation suggests that the activity-dependent release of tau participates in a positive feedback loop on neuronal activity.

CSF tau in APP transgenic mice is increased in an age- dependent manner without a global neuronal loss

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.