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bp(GO:"energy homeostasis")

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Entity

Name
energy homeostasis
Namespace
go
Namespace Version
20181221
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/73688d6dc24e309fca59a1340dc9ee971e9f3baa/external/go-names.belns

Appears in Networks 2

albuquerque2009 v1.0.0

This file encodes the article Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function by Albuquerque et al, 2009

Alzheimer’s disease and the autophagic-lysosomal system v1.0.0

In-Edges 2

a(CHEBI:lipid) regulates bp(GO:"energy homeostasis") View Subject | View Object

In addition to their structural role in membranes, lipids are essential in the maintenance of cellular energy homeostasis as well as regulation of intracellular signaling pathways PubMed:29758300

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a(GO:mitochondrion) regulates bp(GO:"energy homeostasis") View Subject | View Object

Mitochondria are instrumental in the regulation of energy metabolism, and impairment in mitochondrial function has been implicated in the pathogenesis of AD, leading to the mitochondrial cascade hypothesis of AD [121]. PubMed:29758300

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Out-Edges 1

bp(GO:"energy homeostasis") regulates a(CHEBI:"kynurenic acid") View Subject | View Object

Interestingly, astrocytic KYNA production is regulated by neuronal activity (187) and cellular energy metabolism (213). This dependence of extracellular KYNA concentrations on the functional interplay between neurons and astrocytes is in line with the postulated neuromodulatory role of KYNA (418) and adds to the complexity of the neurochemical networks in the brain. PubMed:19126755

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.