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composite(p(HGNC:HSPA8), p(HGNC:STUB1), p(HGNC:UBE2D2))

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Components

Appears in Networks 1

Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system. v1.0.0

In-Edges 0

Out-Edges 4

composite(p(HGNC:HSPA8), p(HGNC:STUB1), p(HGNC:UBE2D2)) hasComponent p(HGNC:HSPA8) View Subject | View Object

Appears in Networks:

composite(p(HGNC:HSPA8), p(HGNC:STUB1), p(HGNC:UBE2D2)) hasComponent p(HGNC:STUB1) View Subject | View Object

Appears in Networks:

composite(p(HGNC:HSPA8), p(HGNC:STUB1), p(HGNC:UBE2D2)) hasComponent p(HGNC:UBE2D2) View Subject | View Object

Appears in Networks:

composite(p(HGNC:HSPA8), p(HGNC:STUB1), p(HGNC:UBE2D2)) increases deg(p(HGNC:MAPT)) View Subject | View Object

Further evidence of UPS-mediated tau degradation came from the identification of the tau E3 ligase, which is the carboxyl terminus of the Hsc70–interacting protein (CHIP)–Hsc70 complex, with UbcH5B as the E2 enzyme (Petrucelli et al., 2004; Shimura et al., 2004). PubMed:23528736

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.