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complex(a(CHEBI:acetylcholine), p(FPLX:CHRN))

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Components

Appears in Networks 1

Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment v1.0.1

In-Edges 1

path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:acetylcholine), p(FPLX:CHRN)) View Subject | View Object

Binding studies performed with the use of [3H]-nicotine and [3H]-ACh showed a significant reduction in nicotine and ACh binding sites in cerebral cortex of patients suffering from AD, demonstrating a decrease of both nAChR and mAChR populations (Gotti et al., 2006a; Paterson and Nordberg, 2000; Perry et al., 1981, 1985, 1987, 1988; Shimohama et al., 1986; Whitehouse et al., 1981, 1982, 1986) PubMed:25514383

Appears in Networks:
Annotations
MeSH
Cerebral Cortex

Out-Edges 2

complex(a(CHEBI:acetylcholine), p(FPLX:CHRN)) hasComponent a(CHEBI:acetylcholine) View Subject | View Object

Appears in Networks:

complex(a(CHEBI:acetylcholine), p(FPLX:CHRN)) hasComponent p(FPLX:CHRN) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.