p(HGNC:ADNP, pmod(MESH:Haploinsufficiency))
to p(HGNC:SLC17A7)
In females, hippocampal VGLUT1 was not affected by the Adnp genotype or NAP treatment (Supplemental Fig. S4A)
p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) causesNoChange p(HGNC:SLC17A7)
77ca0d0edd
In the cerebral cortex, female Adnp+/− mice exhibited significantly reduced VGLUT1 expression, with no effect for NAP (Supplemental Fig. S4B).
p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases p(HGNC:SLC17A7)
14dd21f00f
At the protein level, a significant reduction in VGLUT1 was observed in both the hippocampus (Fig. 4c–e, immunohistochemistry, 4FG, densitometry) and cerebral cortex (Fig. 4h, i, densitometry).
p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases p(HGNC:SLC17A7)
42293761a8
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.