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rxn(reactants(p(HGNC:HBB)), products(a(CHEBI:methemoglobin)))

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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(MESH:"Reactive Oxygen Species") positiveCorrelation rxn(reactants(p(HGNC:HBB)), products(a(CHEBI:methemoglobin))) View Subject | View Object

. In the presence of reactive oxygen species (ROS), Hb is oxidized to methemoglobin (MetHb; Balla et al., 1993), characterized by the change in the oxidative state of the Fe present in the heme molecule from ferrous (Fe+2) to ferric (Fe+3). PubMed:24904418

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Out-Edges 3

rxn(reactants(p(HGNC:HBB)), products(a(CHEBI:methemoglobin))) hasReactant p(HGNC:HBB) View Subject | View Object

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rxn(reactants(p(HGNC:HBB)), products(a(CHEBI:methemoglobin))) hasProduct a(CHEBI:methemoglobin) View Subject | View Object

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rxn(reactants(p(HGNC:HBB)), products(a(CHEBI:methemoglobin))) positiveCorrelation a(MESH:"Reactive Oxygen Species") View Subject | View Object

. In the presence of reactive oxygen species (ROS), Hb is oxidized to methemoglobin (MetHb; Balla et al., 1993), characterized by the change in the oxidative state of the Fe present in the heme molecule from ferrous (Fe+2) to ferric (Fe+3). PubMed:24904418

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Text Location
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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.