complex(GO:"NF-kappaB complex")
to p(HGNC:TNF)
Another known target of NF-κB, TNFα [266, 267] is also up-regulated in the cortex [268], cerebrospinal fluid, and the serum of Alzheimer’s disease patients
complex(GO:"NF-kappaB complex") regulates p(HGNC:TNF)
6393409332
Furthermore, Amyloid-β actuates NF-κB – dependent pro-inflammatory pathways in microglia culminating in TNFα expression and subsequently TNFα effectuated neurotoxicity
complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
48b04157fc
Amyloid-β also induces microglial activation that results in NF-κB – induced expression of pro-inflammatory cytokines such as TNFα, IL1β, IL6, and IL8 from the microglia resulting in neuronal death
complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
9947e025ba
Increased presence of NF-κB mediated IL-1β, IL-6, and TNF-α cytokines have been reported in the affected tissues, serum and CSF of AD patients
complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
8c3ca005ad
We observed that anatabine dose dependently inhibited NFκB activation by TNFα in HEK293 NFκB luciferase reporter cells (Fig. 5) whereas nicotine was ineffective
p(HGNC:TNF) increases act(complex(GO:"NF-kappaB complex"))
653fa3ff36
For instance, the small GTPase Rho and its downstream effector Rho-associated coiled-coil containing protein kinase (ROCK) have been shown to contribute to TNFα induction of NFkB activation (45).
p(HGNC:TNF) increases act(complex(GO:"NF-kappaB complex"))
7b4b002d95
The trophic factors that evoke proliferation of NPC by inducing activation of NF-κB include epidermal growth factor (EGF) [155-161], basic fibroblast growth factor (bFGF) [155-161], vascular endothelial growth factor (VEGF) [162], tumor necrosis factor α (TNFα) [163], and erythropoietin (EPO)
p(HGNC:TNF) increases act(complex(GO:"NF-kappaB complex"))
f3188a76e2
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.