PDPK1

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: PDPK1
Namespace: hgnc
Namespace Version: 20180906
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(MESH:"Reactive Oxygen Species") positiveCorrelation act(p(HGNC:PDPK1)) View Subject | View Object

Furthermore, ROS induction by haem directly depends on signal transduction involving Ga inhibitory protein and phosphoinositide 3-kinase, and partially depends on phospholipase Cb, protein kinase C, the mitogen-activated protein kinases (MAPKs) and Rho kinase in neutrophils (Porto et al, 2007). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): erythrocyte
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

Out-Edges 1

act(p(HGNC:PDPK1)) positiveCorrelation a(MESH:"Reactive Oxygen Species") View Subject | View Object

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): erythrocyte
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.