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a(HM:"Pathogen Associated Molecular Pattern")

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Entity

Name
Pathogen Associated Molecular Pattern
Namespace
HM
Namespace Version
None
Pattern
.*

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 0

Out-Edges 2

a(HM:"Pathogen Associated Molecular Pattern") increases act(p(HGNC:TLR4)) View Subject | View Object

The cause of sepsis is primarily an exaggerated, generalized inflammatory response to an extrinsic stimulus. Mechanistically, so-called PAMPs (pathogen-associated molecular patterns) lead to the activation of pattern recognition receptors (PRRs) such as tolllike receptors (TLRs) and C-type lectin receptors (CLRs) [28, 29]. PubMed:29956069

Appears in Networks:
Annotations
MeSH
Sepsis
Text Location
Review

a(HM:"Pathogen Associated Molecular Pattern") increases act(p(PFAM:"Lectin_C")) View Subject | View Object

The cause of sepsis is primarily an exaggerated, generalized inflammatory response to an extrinsic stimulus. Mechanistically, so-called PAMPs (pathogen-associated molecular patterns) lead to the activation of pattern recognition receptors (PRRs) such as tolllike receptors (TLRs) and C-type lectin receptors (CLRs) [28, 29]. PubMed:29956069

Appears in Networks:
Annotations
MeSH
Sepsis
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.