1. Catalog
  2. Nodes
  3. p(HGNC:MAPT, frag("26_230"))

p(HGNC:MAPT, frag("26_230"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
MAPT
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Tau in physiology and pathology v1.0.0

In-Edges 3

p(HGNC:MAPT) hasVariant p(HGNC:MAPT, frag("26_230")) View Subject | View Object

Appears in Networks:

p(FPLX:Caspase) increases p(HGNC:MAPT, frag("26_230")) View Subject | View Object

This fragment was proposed to be generated by caspases (although not caspase 3). PubMed:26631930

Appears in Networks:

path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, frag("26_230")) View Subject | View Object

For instance, a 20–22-kDa N‑terminal tau fragment (amino acids 26–230) was detected in an AD mouse model expressing a transgenic nerve growth factor (NGF)-specific antibody (AD11) and in the cerebrospinal fluid (CSF) of individuals with AD is neurotoxic in primary neurons PubMed:26631930

Appears in Networks:

Out-Edges 1

p(HGNC:MAPT, frag("26_230")) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

For instance, a 20–22-kDa N‑terminal tau fragment (amino acids 26–230) was detected in an AD mouse model expressing a transgenic nerve growth factor (NGF)-specific antibody (AD11) and in the cerebrospinal fluid (CSF) of individuals with AD is neurotoxic in primary neurons PubMed:26631930

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.