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a(PUBCHEM:129688311)

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Entity

Name
129688311
Namespace
PUBCHEM
Namespace Version
None
Pattern
^\d+$

Appears in Networks 1

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing v1.0.0

In-Edges 0

Out-Edges 3

a(PUBCHEM:129688311) increases bp(GO:"lysosomal lumen acidification") View Subject | View Object

Second, the TFEB inducer 2-hydroxypropyl-β-cyclo- dextrin promoted the acidity of lysosomes in neurons 190 . PubMed:30116051

Appears in Networks:

a(PUBCHEM:129688311) decreases a(HBP:HBP00016) View Subject | View Object

Harnessing TFEB by 2-hydroxypropyl-β-cyclodextrin promoted clearance of proteolipid aggregates and α-syn- uclein in a cellular model of PD 195,204 .It also augmented the elimination of Aβ in a Tg19959/CRND8 mouse model of AD 173 . PubMed:30116051

Appears in Networks:
Annotations
MeSH
Parkinson Disease

a(PUBCHEM:129688311) decreases a(CHEBI:"amyloid-beta") View Subject | View Object

Harnessing TFEB by 2-hydroxypropyl-β-cyclodextrin promoted clearance of proteolipid aggregates and α-syn- uclein in a cellular model of PD 195,204 .It also augmented the elimination of Aβ in a Tg19959/CRND8 mouse model of AD 173 . PubMed:30116051

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.