Complement C5a

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: Complement C5a
Namespace: MeSH
Namespace Version: 20181007
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(CHEBI:heme) increases a(MESH:"Complement C5a") View Subject | View Object

C3a and C5a anaphylatoxins, as well as the soluble membrane attack complex (sC5b9), are generated by incubation of heme with human serum or blood in vitro, via the alternative complement pathway [33,77] (Box 5). PubMed:26875449

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

MeSH: Anemia, Sickle Cell
Text Location: Review

Out-Edges 1

a(MESH:"Complement C5a") increases path(MESH:Hemolysis) View Subject | View Object

However, also the anaphylatoxins C3a and C5a may lead to cellular and organ disturbances [75]. PubMed:29956069

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): erythrocyte
MeSH: Liver
MeSH: Sepsis
Text Location: Review

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.