p(HGNC:UBE2S)
Recent work has shown that the E2s Cdc34 (cell division cycle 34) and Ube2S (ubiquitin-conjugating enzyme E2S) also form noncovalent interfaces with ubiquitin in addition to the covalent thioester bond [23,24], suggesting that E2s catalyze ubiquitin transfer at least in part by holding ubiquitin against an interface on the E2 surface that optimizes the position of the thioester bond in the active site PubMed:24457024
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.