bp(GO:"positive regulation of neuron apoptotic process")
The presence of amyloid deposits, as the main factor leading to damage of the nerve tissue (amyloid hypothesis) has been postulated for over 25 years (recently reviewed in Selkoe and Hardy 2016). PubMed:29196815
AD belongs to a large group of neurodegenerative diseases (NDs) characterized by cognitive impairment and progressive synaptic damage accompanied by neuronal loss. PubMed:29196815
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.