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Entity

Name
positive regulation of neuron apoptotic process
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

In-Edges 2

a(CHEBI:"amyloid-beta") increases bp(GO:"positive regulation of neuron apoptotic process") View Subject | View Object

The presence of amyloid deposits, as the main factor leading to damage of the nerve tissue (amyloid hypothesis) has been postulated for over 25 years (recently reviewed in Selkoe and Hardy 2016). PubMed:29196815

path(MESH:"Alzheimer Disease") increases bp(GO:"positive regulation of neuron apoptotic process") View Subject | View Object

AD belongs to a large group of neurodegenerative diseases (NDs) characterized by cognitive impairment and progressive synaptic damage accompanied by neuronal loss. PubMed:29196815

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.