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  3. a(MESH:"Complement C3a")

a(MESH:"Complement C3a")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Complement C3a
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(CHEBI:heme) increases a(MESH:"Complement C3a") View Subject | View Object

C3a and C5a anaphylatoxins, as well as the soluble membrane attack complex (sC5b9), are generated by incubation of heme with human serum or blood in vitro, via the alternative complement pathway [33,77] (Box 5). PubMed:26875449

Appears in Networks:
Annotations
MeSH
Anemia, Sickle Cell
Text Location
Review

Out-Edges 1

a(MESH:"Complement C3a") increases path(MESH:Hemolysis) View Subject | View Object

However, also the anaphylatoxins C3a and C5a may lead to cellular and organ disturbances [75]. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Sepsis
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.