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Entity

Name
negative regulation of neuron apoptotic process
Namespace
go
Namespace Version
20190207
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/a5b84013a08880975ca84f40999e4404b14a97e2/external/go-names.belns

Appears in Networks 2

In-Edges 2

sec(p(HGNC:APP)) association bp(GO:"negative regulation of neuron apoptotic process") View Subject | View Object

However, it is believed that the secreted form of APP plays important roles in neuronal plasticity and survival (Mattson, 1997). PubMed:12428809

p(FPLX:NFkappaB) association bp(GO:"negative regulation of neuron apoptotic process") View Subject | View Object

In the nervous system, NF-κB has been proposed to serve important function by acting as a transcription regulator: it has roles in inflammation, neuronal survival, differentiation, apoptosis, neurite outgrowth, and synaptic plasticity [5], which are impaired in the progression of various neurodegenerative diseases especially in AD. PubMed:27288790

Out-Edges 2

bp(GO:"negative regulation of neuron apoptotic process") association sec(p(HGNC:APP)) View Subject | View Object

However, it is believed that the secreted form of APP plays important roles in neuronal plasticity and survival (Mattson, 1997). PubMed:12428809

bp(GO:"negative regulation of neuron apoptotic process") association p(FPLX:NFkappaB) View Subject | View Object

In the nervous system, NF-κB has been proposed to serve important function by acting as a transcription regulator: it has roles in inflammation, neuronal survival, differentiation, apoptosis, neurite outgrowth, and synaptic plasticity [5], which are impaired in the progression of various neurodegenerative diseases especially in AD. PubMed:27288790

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.