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path(HP:"autoimmune hemolytic anemia")

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Entity

Name
autoimmune hemolytic anemia
Namespace
HP
Namespace Version
2017-10-05
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/namespace/hp/hp-20171108.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

path(MESH:"Venous Thromboembolism") positiveCorrelation path(HP:"autoimmune hemolytic anemia") View Subject | View Object

In a report of 28 heterogeneous patients with either warm or cold AIHA, 5 of 15 episodes of haemolysis were associated with venous thromboembolism (Hendrick, 2003). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:Thrombosis) association path(HP:"autoimmune hemolytic anemia") View Subject | View Object

Multiple haemolytic disorders and therapeutic interventions produce substantial intravascular haemolysis. Examples include PNH, SCD, thalassaemias, glucose-6-phosphate dehydrogenase (G6PD) deficiency, hereditary spherocytosis and stomatocytosis, pyruvate kinase deficiency, autoimmune haemolytic anaemia, microangiopathies, acute haemolytic transfusion reactions, mechanical circulatory support [e.g., left ventricular assist device (LVAD)/extracorporeal membrane oxygenation (ECMO)], RBC transfusions and infusions of RBC substitutes. These disorders, therapies and procedures are also associated with an increased risk of thrombosis. PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Plasma
MeSH
Urine
Text Location
Review

Out-Edges 4

path(HP:"autoimmune hemolytic anemia") increases path(MESH:Hemolysis) View Subject | View Object

Multiple haemolytic disorders and therapeutic interventions produce substantial intravascular haemolysis. Examples include PNH, SCD, thalassaemias, glucose-6-phosphate dehydrogenase (G6PD) deficiency, hereditary spherocytosis and stomatocytosis, pyruvate kinase deficiency, autoimmune haemolytic anaemia, microangiopathies, acute haemolytic transfusion reactions, mechanical circulatory support [e.g., left ventricular assist device (LVAD)/extracorporeal membrane oxygenation (ECMO)], RBC transfusions and infusions of RBC substitutes. These disorders, therapies and procedures are also associated with an increased risk of thrombosis. PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Plasma
MeSH
Urine
Text Location
Review

path(HP:"autoimmune hemolytic anemia") association path(MESH:Thrombosis) View Subject | View Object

Multiple haemolytic disorders and therapeutic interventions produce substantial intravascular haemolysis. Examples include PNH, SCD, thalassaemias, glucose-6-phosphate dehydrogenase (G6PD) deficiency, hereditary spherocytosis and stomatocytosis, pyruvate kinase deficiency, autoimmune haemolytic anaemia, microangiopathies, acute haemolytic transfusion reactions, mechanical circulatory support [e.g., left ventricular assist device (LVAD)/extracorporeal membrane oxygenation (ECMO)], RBC transfusions and infusions of RBC substitutes. These disorders, therapies and procedures are also associated with an increased risk of thrombosis. PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Plasma
MeSH
Urine
Text Location
Review

path(HP:"autoimmune hemolytic anemia") positiveCorrelation path(MESH:"Venous Thromboembolism") View Subject | View Object

In a report of 28 heterogeneous patients with either warm or cold AIHA, 5 of 15 episodes of haemolysis were associated with venous thromboembolism (Hendrick, 2003). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(HP:"autoimmune hemolytic anemia") decreases bp(MESH:"Erythrocyte Deformability") View Subject | View Object

Other diseases, including -thalassemia, hemolytic anemias caused by RBC antibodies, and hereditary stomatocytosis, also commonly have RBCs with stiff membranes [23]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.