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a(HBP:ST7612AA1)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
ST7612AA1
Namespace
HBP
Namespace Version
20181119
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/90e1cb9e5e882703380c9db8d4915ac6f3cba137/export/hbp-names.belns

Appears in Networks 1

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

In-Edges 0

Out-Edges 1

a(HBP:ST7612AA1) directlyDecreases act(p(FPLX:HDAC)) View Subject | View Object

In conclusion, ST7612AA1, prodrug of ST7464AA1, is the first of a new generation of HDAC inhibitors, very potent, orally administered, and well tolerated. It is a thiol derivative, pan-histone deacetylase inhibitor, active against a broad panel of cancer cell lines and in vivo tumor models. PubMed:27917100

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.