Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Appears in Networks 1

In-Edges 1

Out-Edges 4

p(HGNC:MAPT, var("p.Val277Met")) increases p(HGNC:MAPT, pmod(Ph, Ser, 396)) View Subject | View Object

In add- ition, only FL Tau V337M was phosphorylated at the KXGS motif (Fig. 2A, mid panel, 12E8), S396 and S404 (PHF-1 epitope) (Fig. 2A, lower panel, PHF-1). PubMed:22611162

p(HGNC:MAPT, var("p.Val277Met")) increases p(HGNC:MAPT, pmod(Ph, Ser, 404)) View Subject | View Object

In add- ition, only FL Tau V337M was phosphorylated at the KXGS motif (Fig. 2A, mid panel, 12E8), S396 and S404 (PHF-1 epitope) (Fig. 2A, lower panel, PHF-1). PubMed:22611162

p(HGNC:MAPT, var("p.Val277Met")) increases path(HBP:neurotoxicity) View Subject | View Object

From these data, we conclude that the continued expression of FL Tau V337M and F3DK280 is toxic for the neurons and as a conse- quence, the development of the nervous system is perturbed. PubMed:22611162

p(HGNC:MAPT, var("p.Val277Met")) decreases bp(GO:"nervous system development") View Subject | View Object

From these data, we conclude that the continued expression of FL Tau V337M and F3DK280 is toxic for the neurons and as a conse- quence, the development of the nervous system is perturbed. PubMed:22611162

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.