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p(HGNC:NLRP12)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
NLRP12
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Activation and regulation of the inflammasomes v1.0.0

In-Edges 1

complex(GO:"inflammasome complex") hasComponent p(HGNC:NLRP12) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HGNC:NLRP12) increases bp(GO:"dendritic cell migration") View Subject | View Object

Indeed, NLRP12 can function as a positive regulator of dendritic cell migration or as a negative regulator of non-canonical NFκB signalling20,21, and NLRP6 can negatively regulate innate immunity22. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High

p(HGNC:NLRP12) increases bp(GO:"negative regulation of NIK/NF-kappaB signaling") View Subject | View Object

Indeed, NLRP12 can function as a positive regulator of dendritic cell migration or as a negative regulator of non-canonical NFκB signalling20,21, and NLRP6 can negatively regulate innate immunity22. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.