1. Catalog
  2. Nodes
  3. p(HGNC:APP, frag("672_770"))

p(HGNC:APP, frag("672_770"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
APP
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Identification of a novel aspartic protease (Asp 2) as beta-secretase v1.0.0

In-Edges 2

p(HGNC:APP) hasVariant p(HGNC:APP, frag("672_770")) View Subject | View Object

Appears in Networks:

p(HGNC:BACE1) increases p(HGNC:APP, frag("672_770")) View Subject | View Object

However, while there is a significant increase in the production of CTFb in the presence of wild-type Asp 2, there is no increase in the presence of the mutant enzymes (Fig. 4b). PubMed:10656250

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.