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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:heme) increases r(HGNC:CXCL8) View Subject | View Object

Incubation of neutrophils with 4 mM hemin resulted in an ;2-fold increase in CXCL8 mRNA expression and in a significant increase in released and cell-associated levels of IL-8 protein compared with the nontreated controls or A1AT-treated cells (Fig. 7A–C). PubMed:28716864

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endothelial cell
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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.