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  3. complex(a(GO:"SCF ubiquitin ligase complex"), p(HGNC:UBA2))

complex(a(GO:"SCF ubiquitin ligase complex"), p(HGNC:UBA2))

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Components

Appears in Networks 1

The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

In-Edges 1

p(HGNC:NEDD8) increases complex(a(GO:"SCF ubiquitin ligase complex"), p(HGNC:UBA2)) View Subject | View Object

For example, modification of the Cullin component of the SCF E3 complexes by the ubiquitin-like protein NEDD8 increases the affinity of the ligases to the E2 component of the conjugation machinery PubMed:14556719

Appears in Networks:

Out-Edges 2

complex(a(GO:"SCF ubiquitin ligase complex"), p(HGNC:UBA2)) hasComponent a(GO:"SCF ubiquitin ligase complex") View Subject | View Object

Appears in Networks:

complex(a(GO:"SCF ubiquitin ligase complex"), p(HGNC:UBA2)) hasComponent p(HGNC:UBA2) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.