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a(CHEBI:"insulin (human)")

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Entity

Name
insulin (human)
Namespace
chebi
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/chebi-names.belns

Appears in Networks 2

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 1

a(CHEBI:nicotine) decreases sec(a(CHEBI:"insulin (human)")) View Subject | View Object

Nicotine also suppresses insulin output from the pancreas, which indicates that smokers are usually hyperglycemic (higher blood sugar level) PubMed:28391535

Appears in Networks:
Annotations
MeSH
Pancreas

Out-Edges 1

a(CHEBI:"insulin (human)") regulates p(HGNC:MTOR) View Subject | View Object

Induction of autophagy is generally controlled by the mTOR kinase (mammalian Target of Rapamycin), which is regulated by growth factors (especially insulin) and nutrient levels. PubMed:22908190

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.