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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

a(HM:"stored erythrocytes") positiveCorrelation path(MESH:Pneumonia) View Subject | View Object

Our findings using a mouse model of trauma and hemorrhagic shock with stored blood transfusion and subsequent PAK instillation demonstrate that transfusion with older stored RBCs increases the severity of bacterial pneumonia. PubMed:29522519

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Cell Ontology (CL)
macrophage
Text Location
Discussion

p(MGI:Hpx) negativeCorrelation path(MESH:Pneumonia) View Subject | View Object

Hemopexin improved post-pneumonia survival in mice that underwent massive resuscitation with stored RBCs (Fig 3A). PubMed:29522519

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Out-Edges 2

path(MESH:Pneumonia) negativeCorrelation p(MGI:Hpx) View Subject | View Object

Hemopexin improved post-pneumonia survival in mice that underwent massive resuscitation with stored RBCs (Fig 3A). PubMed:29522519

Appears in Networks:
Annotations
Text Location
Results

path(MESH:Pneumonia) positiveCorrelation a(HM:"stored erythrocytes") View Subject | View Object

Our findings using a mouse model of trauma and hemorrhagic shock with stored blood transfusion and subsequent PAK instillation demonstrate that transfusion with older stored RBCs increases the severity of bacterial pneumonia. PubMed:29522519

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.