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  3. complex(a(MESH:Ubiquitin), p(INTERPRO:"HECT domain"))

complex(a(MESH:Ubiquitin), p(INTERPRO:"HECT domain"))

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Components

Appears in Networks 1

The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

In-Edges 1

p(HGNC:UBA2) increases complex(a(MESH:Ubiquitin), p(INTERPRO:"HECT domain")) View Subject | View Object

For the Homologous to the E6-AP C Terminus (HECT) domain E3s, the ubiquitin is transferred once again from the E2 enzyme to an active site Cys residue on the E3 to generate a third high-energy thiol ester intermediate, ubiquitin-S~E3, prior to its transfer to the ligase bound substrate PubMed:14556719

Appears in Networks:

Out-Edges 2

complex(a(MESH:Ubiquitin), p(INTERPRO:"HECT domain")) hasComponent a(MESH:Ubiquitin) View Subject | View Object

Appears in Networks:

complex(a(MESH:Ubiquitin), p(INTERPRO:"HECT domain")) hasComponent p(INTERPRO:"HECT domain") View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.