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Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

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act(a(CHEBI:"L-dopa")) negativeCorrelation a(CHEBI:"folate(2-)") View Subject | View Object

Folate starvation in the presence of L-dopa resulted in a 200–210% increase in demethylated PP2A levels, and 235–250% increase in p-Tau levels in the dopaminergic neurons, relative to untreated controls maintained in NF medium. PubMed:22764226

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Annotations
Uberon
dopaminergic cell groups

act(a(CHEBI:"L-dopa")) negativeCorrelation a(CHEBI:"folate(2-)") View Subject | View Object

Here, we found that administration of L-dopa led to a significant 5-fold increase in plasma tHcy concentrations, when compared to saline treated mice (Table 1). This L-dopa induced increase in plasma tHcy was significantly greater in mice that had been reared on either low folate (LF) or FD diets (Table 1). PubMed:22764226

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Uberon
blood plasma

Out-Edges 2

a(CHEBI:"folate(2-)") negativeCorrelation act(a(CHEBI:"L-dopa")) View Subject | View Object

Folate starvation in the presence of L-dopa resulted in a 200–210% increase in demethylated PP2A levels, and 235–250% increase in p-Tau levels in the dopaminergic neurons, relative to untreated controls maintained in NF medium. PubMed:22764226

Appears in Networks:
Annotations
Uberon
dopaminergic cell groups

a(CHEBI:"folate(2-)") negativeCorrelation act(a(CHEBI:"L-dopa")) View Subject | View Object

Here, we found that administration of L-dopa led to a significant 5-fold increase in plasma tHcy concentrations, when compared to saline treated mice (Table 1). This L-dopa induced increase in plasma tHcy was significantly greater in mice that had been reared on either low folate (LF) or FD diets (Table 1). PubMed:22764226

Appears in Networks:
Annotations
Uberon
blood plasma

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.