Evidences path(MESH:"Alcohol Drinking") to p(HGNC:ADNP)

In addition, Adnp expression was increased at the 24 h time point in the NAc of female, but not male mouse (one-way ANOVA; females: F(2,9) = 10.87, p < 0.005; post hoc: p < 0.005; males: p > 0.05).

We found no changes in the expression of Adnp in the VTA (p’s > 0.05).

We found that among male mice, Adnp mRNA levels were increased in the dorsal hippocampus after a 24 h alcohol drinking session, but the level returned to baseline (water-drinking controls) after 24 h of withdrawal (Fig. 2b; one-way ANOVA: F(2,13) = 5.32, p < 0.05, post hoc comparisons, p’s < 0.05)

However, in female mice, the expression of Adnp was reduced after a 24-h alcohol-drinking session, and this reduction persisted after a 24-h withdrawal (Fig. 2c; one-way ANOVA: F(2,13) = 7.53, p < 0.01, post hoc comparisons, p’s < 0.05).

No changes in Adnp levels were detected in the VTA or NAc (p’s > 0.05).

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.