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g(HGNC:NLRP3, var("?"))

Orthologies: 0 | Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
NLRP3
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Activation and regulation of the inflammasomes v1.0.0

In-Edges 2

g(HGNC:NLRP3) hasVariant g(HGNC:NLRP3, var("?")) View Subject | View Object

Appears in Networks:

path(MESH:"Cryopyrin-Associated Periodic Syndromes") positiveCorrelation g(HGNC:NLRP3, var("?")) View Subject | View Object

It is known that about 60% of patients with cryopyrin-associated periodic syndrome (CAPS) carry activating mutations in the coding sequence of NLRP3 itself or in other inflammasome components69. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Caspase subgraph

Out-Edges 1

g(HGNC:NLRP3, var("?")) positiveCorrelation path(MESH:"Cryopyrin-Associated Periodic Syndromes") View Subject | View Object

It is known that about 60% of patients with cryopyrin-associated periodic syndrome (CAPS) carry activating mutations in the coding sequence of NLRP3 itself or in other inflammasome components69. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Caspase subgraph

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.