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In-Edges 7

complex(GO:"P-body") negativeCorrelation p(HGNC:BAG4) View Subject | View Object

Thus, BAG4 overexpression disrupted P body organization PubMed:25036637

Out-Edges 7

p(HGNC:BAG4) negativeCorrelation complex(GO:"P-body") View Subject | View Object

Thus, BAG4 overexpression disrupted P body organization PubMed:25036637

p(HGNC:BAG4) increases complex(p(HGNC:BAG4), p(HGNC:DCP1A)) View Subject | View Object

BAG4, in contrast, interacted with three central components of the These three proteins localize to cytoplasmic structures known as processing bodies, or P bodies, which are involved in mRNA decapping, degradation, and translational silencing (Eulalio et al., 2007): DCP1A, EDC3, and DDX6 (Figure 3E) PubMed:25036637

p(HGNC:BAG4) increases complex(p(HGNC:BAG4), p(HGNC:EDC3)) View Subject | View Object

BAG4, in contrast, interacted with three central components of the These three proteins localize to cytoplasmic structures known as processing bodies, or P bodies, which are involved in mRNA decapping, degradation, and translational silencing (Eulalio et al., 2007): DCP1A, EDC3, and DDX6 (Figure 3E) PubMed:25036637

p(HGNC:BAG4) increases complex(p(HGNC:BAG4), p(HGNC:DDX6)) View Subject | View Object

BAG4, in contrast, interacted with three central components of the These three proteins localize to cytoplasmic structures known as processing bodies, or P bodies, which are involved in mRNA decapping, degradation, and translational silencing (Eulalio et al., 2007): DCP1A, EDC3, and DDX6 (Figure 3E) PubMed:25036637

p(HGNC:BAG4) directlyIncreases complex(p(HGNC:BAG4), p(HGNC:HSPB1)) View Subject | View Object

BAG3 and BAG4 showed a strong association only with the small heat shock protein Hsp27 (Figure 5F) and the mRNA decapping complex member DCP1B, respectively (Figure 5G), whereas BAG1 interacted with several proteasome subunits (Figure S4C) PubMed:25036637

p(HGNC:BAG4) directlyIncreases complex(p(HGNC:BAG4), p(HGNC:DCP1B)) View Subject | View Object

BAG3 and BAG4 showed a strong association only with the small heat shock protein Hsp27 (Figure 5F) and the mRNA decapping complex member DCP1B, respectively (Figure 5G), whereas BAG1 interacted with several proteasome subunits (Figure S4C) PubMed:25036637

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.