1. Catalog
  2. Nodes
  3. a(PUBCHEM:442534)

a(PUBCHEM:442534)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
442534
Namespace
PUBCHEM
Namespace Version
None
Pattern
^\d+$

Appears in Networks 1

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease v1.0.0

In-Edges 0

Out-Edges 8

a(PUBCHEM:442534) increases bp(GO:memory) View Subject | View Object

Paeoniflorin improved memory impairments and lowered A accumulation in APP/PS1 trans-genic mice [1]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:442534) decreases a(HBP:"amyloid-beta aggregates") View Subject | View Object

Paeoniflorin improved memory impairments and lowered A accumulation in APP/PS1 trans-genic mice [1]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:442534) decreases path(MESH:"Alzheimer Disease") View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:442534) decreases act(p(FPLX:GSK3)) View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:442534) decreases act(p(FPLX:NFkappaB)) View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:442534) decreases bp(GO:"NLRP3 inflammasome complex assembly") View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:442534) decreases p(HGNC:TNF) View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:442534) decreases p(HGNC:IL1B) View Subject | View Object

It attenuated the development of AD by inhibiting glycogen synthase kinase 3 (GSK-3) and NF-B activation, and sup-pressing the NLRP3 inflammasome and cytokines such as TNF-and IL-1 [1]. PubMed:29179999

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.