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Entity

Name
Tricuspid Valve Insufficiency
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 4

p(HGNC:HP) negativeCorrelation path(MESH:"Tricuspid Valve Insufficiency") View Subject | View Object

The median values and associated interquartile ranges for hmox-1 and haptoglobin show that patients with PE+TR+ had lower expression of these genes compared with patients who were PE+TR− or PE− PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

p(HGNC:ARG1) positiveCorrelation path(MESH:"Tricuspid Valve Insufficiency") View Subject | View Object

Table 3 shows a significant increase in the median value for the plasma biomarker of hemolysis, arginase-1 in patients with PE+TR+ by pairwise comparison using the Kruskal-Wallis test. PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

p(HGNC:HMOX1) negativeCorrelation path(MESH:"Tricuspid Valve Insufficiency") View Subject | View Object

The median values and associated interquartile ranges for hmox-1 and haptoglobin show that patients with PE+TR+ had lower expression of these genes compared with patients who were PE+TR− or PE− PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

p(HGNC:HMOX1) negativeCorrelation path(MESH:"Tricuspid Valve Insufficiency") View Subject | View Object

The inverse correlation between hmox-1 expression in circulating leukocytes and the TR jet velocity in patients with acute PE was significant (r2=0.45, p <0.001), but this significance was absent in patients without PE (r2=0.01, P=0.52). PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Pulmonary Embolism
Text Location
Results

Out-Edges 5

path(MESH:"Tricuspid Valve Insufficiency") causesNoChange g(HGNC:PTGS2) View Subject | View Object

The cyclooxygenase-2 gene was not significantly different between groups and had no correlation with the TR jet velocity in patients with PE (R2=0.03). PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

path(MESH:"Tricuspid Valve Insufficiency") negativeCorrelation p(HGNC:HMOX1) View Subject | View Object

The median values and associated interquartile ranges for hmox-1 and haptoglobin show that patients with PE+TR+ had lower expression of these genes compared with patients who were PE+TR− or PE− PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

path(MESH:"Tricuspid Valve Insufficiency") negativeCorrelation p(HGNC:HMOX1) View Subject | View Object

The inverse correlation between hmox-1 expression in circulating leukocytes and the TR jet velocity in patients with acute PE was significant (r2=0.45, p <0.001), but this significance was absent in patients without PE (r2=0.01, P=0.52). PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Pulmonary Embolism
Text Location
Results

path(MESH:"Tricuspid Valve Insufficiency") negativeCorrelation p(HGNC:HP) View Subject | View Object

The median values and associated interquartile ranges for hmox-1 and haptoglobin show that patients with PE+TR+ had lower expression of these genes compared with patients who were PE+TR− or PE− PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

path(MESH:"Tricuspid Valve Insufficiency") positiveCorrelation p(HGNC:ARG1) View Subject | View Object

Table 3 shows a significant increase in the median value for the plasma biomarker of hemolysis, arginase-1 in patients with PE+TR+ by pairwise comparison using the Kruskal-Wallis test. PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.