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bp(GO:"GO:0008292")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
GO:0008292
Namespace
go
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/go.belns

Appears in Networks 1

Interplay of neurotransmitters in Alzheimer's disease v1.0.0

In-Edges 2

path(MESH:D000544) decreases bp(GO:"GO:0008292") View Subject | View Object

Furthermore, synaptic reuptake of choline, which is essential for the synthesis of ACh molecules that are to be released into the synaptic cleft in subsequent rounds of neurotransmission, is reduced to -60% of normal levels in Alzheimer's disease, and direct measurement reveals that levels of ACh synthesis are reduced by one half in affected patients. PubMed:16273023

Appears in Networks:
Annotations
Disease Ontology (DO)
Alzheimer's disease

path(MESH:D003704) association bp(GO:"GO:0008292") View Subject | View Object

In fact, it has been demonstrated that decreasing levels of ACh synthesis are significantly correlated with increasing severity of dementia in patients with Alzheimer's disease (Table) PubMed:16273023

Appears in Networks:
Annotations
Disease Ontology (DO)
Alzheimer's disease

Out-Edges 1

bp(GO:"GO:0008292") association path(MESH:D003704) View Subject | View Object

In fact, it has been demonstrated that decreasing levels of ACh synthesis are significantly correlated with increasing severity of dementia in patients with Alzheimer's disease (Table) PubMed:16273023

Appears in Networks:
Annotations
Disease Ontology (DO)
Alzheimer's disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.