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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:heme) decreases p(HGNC:SELL) View Subject | View Object

Exposure of washed human peripheral blood leukocytes to protein free crystalline heme that has been dissolved in NaOH (100 mmolL1) with subsequent adjustment to pH 7.8 resulted in a drastic reduction in cell surface CD62L expression on CD14 low CD15 high neutrophil granulocytes after 30 minutes of exposure (Figure 1A). PubMed:29610666

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neutrophil
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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.