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p(HGNC:FLT1)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
FLT1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 2

Screening of a neuronal cell model of Tau pathology for therapeutic compounds v1.0.0

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

p(HGNC:AMBP) decreases p(HGNC:FLT1) View Subject | View Object

Treatment of starved ewes with A1M up-regulated the expression of SOD2 (p,0.043) and down-regulated the expression of s-Flt1 (p,0.012), in blood (Figure 11). PubMed:24489717

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Blood
Text Location
Results

Out-Edges 1

act(p(HGNC:FLT1)) increases a(HBP:"Tau aggregates") View Subject | View Object

The dose response screening identified compounds related to the inhibition of 3 major targets led to inhibition of Tau aggregation: p38 MAPK (7 out of 8 compounds in the initial library), VEGFR1/2 (3 of 8) and TGF (3 of 10). PubMed:30640040

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.