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rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite)))

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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(MESH:"Salivary Glands") increases rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite))) View Subject | View Object

Third, during surgery, patients were intratracheally intubated, which prevented swallowing of saliva, which may have interrupted the nitrate-tonitrite pathway, thus contributing to the observed decrease in nitrite. PubMed:27308950

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MeSH
Plasma
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Discussion

a(MESH:"Salivary Glands") increases rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite))) View Subject | View Object

Studies have shown that nitrate concentrates in saliva and is reduced to nitrite by mouth commensal bacterial nitrate reductase and then nitrite is reduced to NO under acidic conditions of the stomach. 28,51,52 PubMed:27308950

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MeSH
Saliva
MeSH
Hypoxia
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rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite))) hasReactant a(CHEBI:nitrate) View Subject | View Object

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rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite))) hasProduct a(CHEBI:nitrite) View Subject | View Object

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.