CD40LG

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: CD40LG
Namespace: hgnc
Namespace Version: 20180906
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(MESH:"Adenosine Diphosphate") increases p(HGNC:CD40LG) View Subject | View Object

ADP released from haemolysed RBCs induces CD40LG release from platelets and lymphocytes, thereby contributing to the pro-inflammatory and pro-thrombotic environment (Helms et al, 2013). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

Out-Edges 3

p(HGNC:CD40LG) increases a(MESH:Cytokines) View Subject | View Object

Furthermore, haem-induced release of P-selectin and VWF is mediated by TLR4 and NFkB signalling. PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

p(HGNC:CD40LG) increases a(MESH:"Cell Adhesion Molecules") View Subject | View Object

Furthermore, haem-induced release of P-selectin and VWF is mediated by TLR4 and NFkB signalling. PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

p(HGNC:CD40LG) increases path(MESH:"Blood Coagulation") View Subject | View Object

Furthermore, haem-induced release of P-selectin and VWF is mediated by TLR4 and NFkB signalling. PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.