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a(CHEBI:hexadecanoate)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
hexadecanoate
Namespace
chebi
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/chebi-names.belns

Appears in Networks 1

The role of inflammasome in Alzheimer’s disease v1.0.3

In-Edges 2

composite(a(CHEBI:hexadecanoate), p(HGNC:NLRC4)) hasComponent a(CHEBI:hexadecanoate) View Subject | View Object

Appears in Networks:

composite(a(CHEBI:hexadecanoate), p(HGNC:PYCARD)) hasComponent a(CHEBI:hexadecanoate) View Subject | View Object

Appears in Networks:

Out-Edges 2

a(CHEBI:hexadecanoate) increases complex(GO:"IPAF inflammasome complex") View Subject | View Object

Palmitate, a fatty acid, activates the NLRC4 inflammasome in primary astrocytes leading to the release of IL-1β (Liu and Chan, 2014) PubMed:24561250

Appears in Networks:
Annotations
Cell Ontology (CL)
astrocyte
Confidence
High
NeuroMMSigDB
Interleukin signaling subgraph

a(CHEBI:hexadecanoate) increases act(complex(GO:"IPAF inflammasome complex")) View Subject | View Object

Recently we identify that palmitate activates the NLRC4 inflammasome in primary astrocytes to release IL-1β, and ASC participates in the activation of the NLRC4 inflammasome (Liu and Chan, 2014) PubMed:24561250

Appears in Networks:
Annotations
Cell Ontology (CL)
astrocyte
Confidence
Medium
NeuroMMSigDB
Interleukin signaling subgraph

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.