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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:heme) decreases p(MGI:Col1a1) View Subject | View Object

Interestingly, besides the common cluster of upregulated proteins, which includes Sqstm1, ubiquitin, and a number of heat shock and oxidative defence proteins, we also observed that heme strongly suppressed the abundance of collagen (Col1a1) 1 protein. PubMed:25301065

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.