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a(HBP:"Tau antibody, Tau46")

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Entity

Name
Tau antibody, Tau46
Namespace
HBP
Namespace Version
20181128
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/7e4be528f12abd28be768b62402fba6e083eaf9e/export/hbp-names.belns

Appears in Networks 1

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro v1.0.0

This file encodes the article Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro by Nobuhara et. al. 2017

In-Edges 1

p(HGNC:MAPT) association a(HBP:"Tau antibody, Tau46") View Subject | View Object

Tau46 was the only antibody that did not show a statistically significant reduction in neuronal tau uptake (Figure 4, B and C). Tau46 bound with high apparent affinity to both recombinant and paired helical filament tau by ELISA (Table 2), demonstrating the binding of the antibody to full-length tau. PubMed:28408124

Appears in Networks:
Annotations
MeSH
Alzheimer Disease
Text Location
Results

Out-Edges 2

a(HBP:"Tau antibody, Tau46") causesNoChange tloc(p(HGNC:MAPT), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) View Subject | View Object

Tau46 was the only antibody that did not show a statistically significant reduction in neuronal tau uptake (Figure 4, B and C). Tau46 bound with high apparent affinity to both recombinant and paired helical filament tau by ELISA (Table 2), demonstrating the binding of the antibody to full-length tau. PubMed:28408124

Appears in Networks:
Annotations
MeSH
Alzheimer Disease
Text Location
Results

a(HBP:"Tau antibody, Tau46") association p(HGNC:MAPT) View Subject | View Object

Tau46 was the only antibody that did not show a statistically significant reduction in neuronal tau uptake (Figure 4, B and C). Tau46 bound with high apparent affinity to both recombinant and paired helical filament tau by ELISA (Table 2), demonstrating the binding of the antibody to full-length tau. PubMed:28408124

Appears in Networks:
Annotations
MeSH
Alzheimer Disease
Text Location
Results

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.