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Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

p(MGI:Il1b) positiveCorrelation act(p(MGI:Pycard)) View Subject | View Object

Knockdown of ASC significantly inhibits the secretion of IL-1b, which primarily suggests that Inflammation/ASC axis is involved in the heme-mediated maturation and secretion of IL-1b (Fig. 2b). PubMed:24464629

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

Out-Edges 1

act(p(MGI:Pycard)) positiveCorrelation p(MGI:Il1b) View Subject | View Object

Knockdown of ASC significantly inhibits the secretion of IL-1b, which primarily suggests that Inflammation/ASC axis is involved in the heme-mediated maturation and secretion of IL-1b (Fig. 2b). PubMed:24464629

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.