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p(MGI:Mapt, pmod(Ph, Ser, 262), pmod(Ph, Ser, 356))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Mapt
Namespace
mgi
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/mgi-names.belns

Appears in Networks 1

Adenosine A1 receptor antagonist 64627 alleviates axonopathy caused by human Tau ΔK280 v1.0.0

In-Edges 1

p(MGI:Mapt) hasVariant p(MGI:Mapt, pmod(Ph, Ser, 262), pmod(Ph, Ser, 356)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(MGI:Mapt, pmod(Ph, Ser, 262), pmod(Ph, Ser, 356)) decreases complex(a(GO:microtubule), p(MGI:Mapt)) View Subject | View Object

Phosphorylation of these serines is known to induce detachment of Tau from microtubules and to promote missorting of Tau (17). PubMed:27671637

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.