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a(GO:"Pick body")

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Entity

Name
Pick body
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 2

Analysis of Isoform-specific Tau Aggregates Suggests a Common Toxic Mechanism Involving Similar Pathological Conformations and Axonal Transport Inhibition v1.0.1

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 5

a(HBP:"Tau oligomers") association a(GO:"Pick body") View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

a(HBP:"phosphatase-activating domain") association a(GO:"Pick body") View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

p(HGNC:MAPT) association a(GO:"Pick body") View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

a(MESH:Ubiquitin) association a(GO:"Pick body") View Subject | View Object

The DF2 immunoreactivity of Lewy bodies led us to search for similar DF2-positive inclusions, and we found that Lewy-like bodies in motor neurons in amyotrophic lateral sclerosis (ALS; Murayama et al. 1990a) and Pick bodies in Pick’s disease (Murayama et al. 1990b) were strongly reactive; the latter stained also for tau, whereas the former stained neither for tau nor a-synuclein. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Niemann-Pick Diseases

p(HGNC:MAPT) association a(GO:"Pick body") View Subject | View Object

The DF2 immunoreactivity of Lewy bodies led us to search for similar DF2-positive inclusions, and we found that Lewy-like bodies in motor neurons in amyotrophic lateral sclerosis (ALS; Murayama et al. 1990a) and Pick bodies in Pick’s disease (Murayama et al. 1990b) were strongly reactive; the latter stained also for tau, whereas the former stained neither for tau nor a-synuclein. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Niemann-Pick Diseases

Out-Edges 5

a(GO:"Pick body") association a(HBP:"Tau oligomers") View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

a(GO:"Pick body") association a(HBP:"phosphatase-activating domain") View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

a(GO:"Pick body") association p(HGNC:MAPT) View Subject | View Object

Similarly, the characteristic Pick bodies in the frontal cortex were well labeled by TNT1, TOC1 and R1 in PiD tissue (Fig. 5M–P) PubMed:27574109

Appears in Networks:
Annotations
MeSH
Frontal Lobe
MeSH
Pick Disease of the Brain

a(GO:"Pick body") association p(HGNC:MAPT) View Subject | View Object

The DF2 immunoreactivity of Lewy bodies led us to search for similar DF2-positive inclusions, and we found that Lewy-like bodies in motor neurons in amyotrophic lateral sclerosis (ALS; Murayama et al. 1990a) and Pick bodies in Pick’s disease (Murayama et al. 1990b) were strongly reactive; the latter stained also for tau, whereas the former stained neither for tau nor a-synuclein. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Niemann-Pick Diseases

a(GO:"Pick body") association a(MESH:Ubiquitin) View Subject | View Object

The DF2 immunoreactivity of Lewy bodies led us to search for similar DF2-positive inclusions, and we found that Lewy-like bodies in motor neurons in amyotrophic lateral sclerosis (ALS; Murayama et al. 1990a) and Pick bodies in Pick’s disease (Murayama et al. 1990b) were strongly reactive; the latter stained also for tau, whereas the former stained neither for tau nor a-synuclein. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Niemann-Pick Diseases

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.