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Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

p(HGNC:SLC48A1) positiveCorrelation bp(GO:"heme transport") View Subject | View Object

Expression of zebrafish hrg1a and hrg1b rescued growth of hem1Δ yeast at heme concentrations as low as 0.25 μM, comparable to the established heme transporters CeHRG-4 and CeHRG-1, demonstrating that Hrg1a and Hrg1b are heme transporters (Fig 1G) [10]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Results

p(HGNC:SLC48A1) positiveCorrelation bp(GO:"heme transport") View Subject | View Object

We show that the zebrafish kidney is the primary organ for heme-iron recycling during EP and that zebrafish Hrg1a and Hrg1b are heme transporters that are expressed and upregulated in kidney macrophages after PHZ-induced hemolysis. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

Out-Edges 2

bp(GO:"heme transport") positiveCorrelation p(HGNC:SLC48A1) View Subject | View Object

Expression of zebrafish hrg1a and hrg1b rescued growth of hem1Δ yeast at heme concentrations as low as 0.25 μM, comparable to the established heme transporters CeHRG-4 and CeHRG-1, demonstrating that Hrg1a and Hrg1b are heme transporters (Fig 1G) [10]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Results

bp(GO:"heme transport") positiveCorrelation p(HGNC:SLC48A1) View Subject | View Object

We show that the zebrafish kidney is the primary organ for heme-iron recycling during EP and that zebrafish Hrg1a and Hrg1b are heme transporters that are expressed and upregulated in kidney macrophages after PHZ-induced hemolysis. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Kidney
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.