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  3. a(MESH:"Cations, Divalent")

a(MESH:"Cations, Divalent")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Cations, Divalent
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/73ec5665b99a7a4b84edd84bbd46b34fac335358/external/mesh-names.belns

Appears in Networks 2

Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System v1.0.0

Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine v1.0.1

In-Edges 4

p(FPLX:CHRN) increases tloc(a(MESH:"Cations, Divalent"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) View Subject | View Object

Mammalian nAChRs are cation selective, being permeable to small monovalent and divalent cations. PubMed:17009926

Appears in Networks:

p(FPLX:CHRN) increases tloc(a(MESH:"Cations, Divalent"), fromLoc(MESH:"Intracellular Space"), toLoc(MESH:"Extracellular Space")) View Subject | View Object

Mammalian nAChRs are cation selective, being permeable to small monovalent and divalent cations. PubMed:17009926

Appears in Networks:

p(FPLX:CHRN) increases tloc(a(MESH:"Cations, Divalent"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) View Subject | View Object

Mammalian nAChRs are cation selective, being permeable to small monovalent and divalent cations that can fit through the narrowest hydro- philic region of the open pore (Albuquerque et al., 2009; Dani, 1989; Dani & Bertrand, 2007; Dani & Eisenman, 1987). PubMed:26472524

Appears in Networks:

p(FPLX:CHRN) increases tloc(a(MESH:"Cations, Divalent"), fromLoc(MESH:"Intracellular Space"), toLoc(MESH:"Extracellular Space")) View Subject | View Object

Mammalian nAChRs are cation selective, being permeable to small monovalent and divalent cations that can fit through the narrowest hydro- philic region of the open pore (Albuquerque et al., 2009; Dani, 1989; Dani & Bertrand, 2007; Dani & Eisenman, 1987). PubMed:26472524

Appears in Networks:

Out-Edges 1

tloc(a(MESH:"Cations, Divalent"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases bp(GO:"membrane depolarization") View Subject | View Object

While nAChR activity causes depolarization, the divalent cation permeability plays an impor- tant physiological role by supplying ionic signals, including calcium (Bertrand, Galzi, Devillers-Thiery, Bertrand, & Changeux, 1993b; Dani & Bertrand, 2007; Decker & Dani, 1990; Gray, Rajan, Radcliffe, Yakehiro, & Dani, 1996; McGehee, Heath, Gelber, Devay, & Role, 1995; Vernino et al., 1992). PubMed:26472524

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.